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The Tittabawassee River is a stream which flows in a generally southward direction through the Lower Peninsula of the U.S. state of Michigan. The river rises in Roscommon County. From there it flows through Gladwin, Midland and Saginaw counties where, as a major tributary of the Saginaw River it flows into it at Saginaw. Some of its tributaries include the Chippewa, Pine, and Tobacco rivers. Significant communities located on or near the Tittabawassee River include Saginaw, Midland, Sanford and Beaverton. In Saginaw County, the river flows through Tittabawassee Township which is named for the river and contains the unincorporated community of Freeland.